Standard

height (minimum, inv-normal transformed)

near GH2 · rs2727311

Where this position leads

Condition: Height

rs2727311 Condition: Height Height Condition rs2727311 rs2727311 near GH2

What the study found

Who was studied 119,012 African American or Afro-Caribbean individuals, 57,810 Hispanic or Latin American individuals, 6,384 East Asian ancestry individuals, 424,306 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0734 lower (95% confidence interval 0.066-0.081); p = 5 × 10−80.

How common The G allele had a frequency of about 66% in the people studied.

Where it sits Chromosome 17, band 17q23.3 — between genes, 3.8 kb from GH2.

What each result means

A/A No copy of the version the research linked to height (minimum, inv-normal transformed). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to height (minimum, inv-normal transformed). That is a smaller link than two copies.
G/G Two copies of the version the research linked to height (minimum, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2727311

What is rs2727311?

rs2727311 is a single position in the genome, in or near the near GH2 gene. Published research associates it with height (minimum, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2727311 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs2727311 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2727311 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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height (minimum, inv-normal transformed) (rs2727311). MyGeneLog™. https://www.mygenelog.com/variants/rs2727311

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