Who was studied 7,177 European ancestry cases, 1,059,740 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.0589 lower (95% confidence interval 0.046-0.071); p = 4 × 10−20.
How common The A allele had a frequency of about 69% in the people studied.
Where it sits Chromosome 8, band 8p21.1 — in an intron of SCARA5.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Venous thromboembolism compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Venous thromboembolism.
G/GPublished research associates this genotype with typical/baseline likelihood of Venous thromboembolism — no copies of the reported risk allele.
rs2726950 is a single position in the genome, in or near the SCARA5 gene. Published research associates it with venous thromboembolism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2726950 linked to?
On MyGeneLog this position is linked to Venous Thromboembolism. The research behind each link, and its sources, are set out on that condition page.
Does having rs2726950 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2726950 come from?
GWAS Catalog, Circulation 2022, PMID:36154123. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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