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Hyperuricemia in low protein intake

PKD2 · rs2725234

What the study found

Who was studied 47,072 Korean ancestry individuals.

The effect Each copy of the T allele carried 1.34 times the odds of Hyperuricemia in low protein intake (95% confidence interval 1.26-1.42); p = 2 × 10−20.

Where it sits Chromosome 4, band 4q22.1 — in an intron of PKD2.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Hyperuricemia in low protein intake — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hyperuricemia in low protein intake.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hyperuricemia in low protein intake compared to the general population.
Source

Questions about rs2725234

What is rs2725234?

rs2725234 is a single position in the genome, in or near the PKD2 gene. Published research associates it with hyperuricemia in low protein intake. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2725234 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2725234 come from?

GWAS Catalog, Scientific reports 2025, PMID:40835619. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hyperuricemia in low protein intake (rs2725234). MyGeneLog™. https://www.mygenelog.com/variants/rs2725234

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