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Lymphocyte count

ST8SIA4 · rs2725117

What the study found

Who was studied 524,923 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0146 SD unit higher (95% confidence interval 0.011-0.019); p = 4 × 10−13.

How common The C allele had a frequency of about 61% in the people studied.

Where it sits Chromosome 5, band 5q21.1 — in an intron of ST8SIA4.

What each result means

A/A No copy of the version the research linked to Lymphocyte count. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Lymphocyte count. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Lymphocyte count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2725117

What is rs2725117?

rs2725117 is a single position in the genome, in or near the ST8SIA4 gene. Published research associates it with lymphocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2725117 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2725117 come from?

GWAS Catalog, Cell 2020, PMID:32888493. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lymphocyte count (rs2725117). MyGeneLog™. https://www.mygenelog.com/variants/rs2725117

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