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Who was studied 510,795 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0607 lower (95% confidence interval 0.043-0.079); p = 4 × 10−11.
How common The C allele had a frequency of about 18% in the people studied.
Where it sits Chromosome 7, band 7p15.3 — in an intron of GSDME.
What each result means
C/CTwo copies of the version the research linked to Noncognitive aspects of educational attainment. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Noncognitive aspects of educational attainment. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Noncognitive aspects of educational attainment. This is the starting point the study compared everyone against.
Nature genetics · 2021 · PMID 33414549 · open access
Questions about rs2721796
What is rs2721796?
rs2721796 is a single position in the genome, in or near the GSDME gene. Published research associates it with noncognitive aspects of educational attainment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2721796 linked to?
On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.
Does having rs2721796 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2721796 come from?
GWAS Catalog, Nature genetics 2021, PMID:33414549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 12129Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others9Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Noncognitive aspects of educational attainment (rs2721796). MyGeneLog™. https://www.mygenelog.com/variants/rs2721796