Who was studied 11,599 European ancestry cases, 199,628 European ancestry controls, 5,672 East Asian ancestry cases, 84,660 East Asian ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0866 lower (95% confidence interval 0.063-0.111); p = 1 × 10−12.
Where it sits Chromosome 7, band 7p21.1 — in an intron of LINC01162.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Prostate cancer — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Prostate cancer.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Prostate cancer compared to the general population.
rs2709729 is a single position in the genome, in or near the LINC01162 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2709729 linked to?
On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs2709729 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2709729 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Prostate cancer (rs2709729). MyGeneLog™. https://www.mygenelog.com/variants/rs2709729