LINC01122 · rs2708146
Where this position leads
Condition: Neuroticism
What the study found
Who was studied 270,059 British ancestry individuals.
The effect Each copy of the A allele shifted the measure 0.00787 lower (95% confidence interval 0.0052-0.0105); p = 7 × 10−9.
Where it sits Chromosome 2, band 2p16.1 — in an intron of LINC01122.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs2708146 is a single position in the genome, in or near the LINC01122 gene. Published research associates it with worry/vulnerability (special factor of neuroticism). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.
Subjects that appear in the title or abstract of the same papers as this rsID include brain and memory (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Mol Psychiatry 2019, PMID:30867560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Worry/vulnerability (special factor of neuroticism) (rs2708146). MyGeneLog™. https://www.mygenelog.com/variants/rs2708146