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Who was studied 372,047 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 10.7 z score lower; p = 1 × 10−26.
How common The A allele had a frequency of about 22% in the people studied.
Where it sits Chromosome 17, band 17q21.31 — between genes, 2.8 kb from MAPK8IP1P1.
What each result means
A/ATwo copies of the version the research linked to Feeling hurt. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Feeling hurt. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Feeling hurt. This is the starting point the study compared everyone against.
Nature communications · 2018 · PMID 29500382 · open access
Questions about rs2696668
What is rs2696668?
rs2696668 is a single position in the genome, in or near the near MAPK8IP1P1 gene. Published research associates it with feeling hurt. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2696668 linked to?
On MyGeneLog this position is linked to Irritable Mood. The research behind each link, and its sources, are set out on that condition page.
Does having rs2696668 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2696668 come from?
GWAS Catalog, Nature communications 2018, PMID:29500382. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 8224Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others4Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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