Sensitive

Barrett's esophagus or Esophageal adenocarcinoma

near RNU6-281P · rs2687197

What the study found

Who was studied 16,790 European ancestry cases, 32,476 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.111 higher (95% confidence interval 0.08-0.142); p = 3 × 10−12.

How common The T allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 3, band 3p13 — between genes, 64.7 kb from RNU6-281P.

What each result means

C/C No copy of the version the research linked to Barrett's esophagus or Esophageal adenocarcinoma. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Barrett's esophagus or Esophageal adenocarcinoma. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Barrett's esophagus or Esophageal adenocarcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2687197

What is rs2687197?

rs2687197 is a single position in the genome, in or near the near RNU6-281P gene. Published research associates it with barrett's esophagus or esophageal adenocarcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2687197 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2687197 come from?

GWAS Catalog, Gut 2023, PMID:35882562. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Barrett's esophagus or Esophageal adenocarcinoma (rs2687197). MyGeneLog™. https://www.mygenelog.com/variants/rs2687197

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