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Coronary dominance (left or co-dominant vs right dominant)

near LINC00841 · rs268287

What the study found

Who was studied 7,708 European ancestry left or co-dominant individuals, 37,613 European ancestry right dominant individuals.

The effect Each copy of the A allele carried 1.15 times the odds of Coronary dominance (left or co-dominant vs right dominant) (95% confidence interval 1.1-1.2); p = 3 × 10−10.

How common The A allele had a frequency of about 19% in the people studied.

Where it sits Chromosome 10, band 10q11.21 — between genes, 87.5 kb from LINC00841.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Coronary dominance (left or co-dominant vs right dominant) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Coronary dominance (left or co-dominant vs right dominant).
G/G Published research associates this genotype with typical/baseline likelihood of Coronary dominance (left or co-dominant vs right dominant) — no copies of the reported risk allele.
Source

Questions about rs268287

What is rs268287?

rs268287 is a single position in the genome, in or near the near LINC00841 gene. Published research associates it with coronary dominance (left or co-dominant vs right dominant). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs268287 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs268287 come from?

GWAS Catalog, Cell 2025, PMID:40049164. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Coronary dominance (left or co-dominant vs right dominant) (rs268287). MyGeneLog™. https://www.mygenelog.com/variants/rs268287

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