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Psoriasis vulgaris

CAMK2G · rs2675669

Where this position leads

Condition: Psoriasis

rs2675669 Condition: Psoriasis Psoriasis Condition rs2675669 rs2675669 CAMK2G

What the study found

Who was studied 4,007 European ancestry cases, 4,934 European ancestry controls; replicated in up to 9,075 European ancestry cases, up to European ancestry 12,726 controls.

The effect The reported allele is T; the catalogue records no effect size ; p = 4 × 10−11.

How common The T allele had a frequency of about 57% in the people studied.

Where it sits Chromosome 10, band 10q22.2 — between genes, 14 kb from C10orf55.

What each result means

C/C No copy of the version the research linked to Psoriasis vulgaris. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Psoriasis vulgaris. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Psoriasis vulgaris. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2675669

What is rs2675669?

rs2675669 is a single position in the genome, in or near the CAMK2G gene. Published research associates it with psoriasis vulgaris. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2675669 linked to?

On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.

Does having rs2675669 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2675669 come from?

GWAS Catalog, American journal of human genetics 2015, PMID:26626624. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Psoriasis vulgaris (rs2675669). MyGeneLog™. https://www.mygenelog.com/variants/rs2675669

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