Standard

Self-reported math ability (MTAG)

near RPL21P59 · rs26443

Where this position leads

Condition: Educational Attainment

rs26443 Condition: Educational Attainment Educational Attainment Condition rs26443 rs26443 near RPL21P59

What the study found

Who was studied 670,471 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0144 lower (95% confidence interval 0.01-0.018); p = 1 × 10−12.

How common The A allele had a frequency of about 74% in the people studied.

Where it sits Chromosome 5, band 5q34 — between genes, 41.7 kb from RPL21P59.

What each result means

A/A Two copies of the version the research linked to Self-reported math ability (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Self-reported math ability (MTAG). That is a smaller link than two copies.
G/G No copy of the version the research linked to Self-reported math ability (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs26443

What is rs26443?

rs26443 is a single position in the genome, in or near the near RPL21P59 gene. Published research associates it with self-reported math ability (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs26443 linked to?

On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.

Does having rs26443 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs26443 come from?

GWAS Catalog, Nature genetics 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Self-reported math ability (MTAG) (rs26443). MyGeneLog™. https://www.mygenelog.com/variants/rs26443

← See all variants