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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 9541 European ancestry individuals, 1,115 Cilento (founder/genetic isolated) individuals, 897 Ogliastran (founder/genetic isolated) individuals, 1,759 Val Borbera (founder/genetic isolated) individuals; replicated in 2,141 European ancestry individuals, 659 Sorbian (founder/genetic isolated) individuals.
The effect
Each copy of the T allele shifted the measure 0.11 higher (95% confidence interval 0.075-0.145); p = 6 × 10−10.
How common The T allele had a frequency of about 91% in the people studied.
Where it sits Chromosome 18, band 18q22.3 — in an intron of PTGR3.
What each result means
C/CNo copy of the version the research linked to Vascular endothelial growth factor levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Vascular endothelial growth factor levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Vascular endothelial growth factor levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
PLoS genetics · 2016 · PMID 26910538 · open access
Questions about rs2639990
What is rs2639990?
rs2639990 is a single position in the genome, in or near the ZADH2 gene. Published research associates it with vascular endothelial growth factor levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2639990 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2639990 come from?
GWAS Catalog, PLoS genetics 2016, PMID:26910538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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