mean platelet volume (MPV, maximum, inv-norm transformed)
LRRK2 · rs2638272
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 97,007 African American or Afro-Caribbean individuals, 40,412 Hispanic or Latin American individuals, 3,825 East Asian ancestry individuals, 335,593 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0291 lower (95% confidence interval 0.022-0.036); p = 1 × 10−16.
How common The G allele had a frequency of about 40% in the people studied.
Where it sits Chromosome 12, band 12q12 — in an intron of LRRK2.
What each result means
A/ANo copy of the version the research linked to mean platelet volume (MPV, maximum, inv-norm transformed). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to mean platelet volume (MPV, maximum, inv-norm transformed). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to mean platelet volume (MPV, maximum, inv-norm transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs2638272
What is rs2638272?
rs2638272 is a single position in the genome, in or near the LRRK2 gene. Published research associates it with mean platelet volume (mpv, maximum, inv-norm transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2638272 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2638272 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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mean platelet volume (MPV, maximum, inv-norm transformed) (rs2638272). MyGeneLog™. https://www.mygenelog.com/variants/rs2638272