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Dehydroepiandrosterone sulphate levels

SULT2A1 · rs2637125

What the study found

Who was studied 14,846 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.09 umol/L lower (95% confidence interval 0.07-0.11); p = 3 × 10−19.

How common The A allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 19, band 19q13.33 — between genes, 12.3 kb from SULT2A1.

What each result means

A/A Two copies of the version the research linked to Dehydroepiandrosterone sulphate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Dehydroepiandrosterone sulphate levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Dehydroepiandrosterone sulphate levels. This is the starting point the study compared everyone against.
Source

Questions about rs2637125

What is rs2637125?

rs2637125 is a single position in the genome, in or near the SULT2A1 gene. Published research associates it with dehydroepiandrosterone sulphate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2637125 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2637125 come from?

GWAS Catalog, PLoS genetics 2011, PMID:21533175. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Dehydroepiandrosterone sulphate levels (rs2637125). MyGeneLog™. https://www.mygenelog.com/variants/rs2637125

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