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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 9,869 European ancestry individuals, 1,363 African American individuals, 623 Chinese American individuals, 1,082 Hispanic American individuals; replicated in 12,177 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.1 higher (95% confidence interval 0.08-0.12); p = 6 × 10−15.
How common The A allele had a frequency of about 50% in the people studied.
Where it sits Chromosome 10, band 10q22.2 — between genes, 11.1 kb from C10orf55.
What each result means
A/ATwo copies of the version the research linked to Soluble urokinase plasminogen activator receptor levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Soluble urokinase plasminogen activator receptor levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Soluble urokinase plasminogen activator receptor levels. This is the starting point the study compared everyone against.
The Journal of clinical investigation · 2022 · PMID 36194491 · open access
Questions about rs2633321
What is rs2633321?
rs2633321 is a single position in the genome, in or near the near C10orf55 gene. Published research associates it with soluble urokinase plasminogen activator receptor levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2633321 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2633321 come from?
GWAS Catalog, The Journal of clinical investigation 2022, PMID:36194491. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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