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Atrial fibrillation

HCFC2 · rs2629755

Where this position leads

Condition: Atrial Fibrillation

rs2629755 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs2629755 rs2629755 HCFC2

What the study found

Who was studied 77,690 European ancestry cases, 1,167,040 European ancestry controls, 67,864 Japanese ancestry cases, 1,026,594 Japanese ancestry controls.

The effect Each copy of the G allele shifted the measure 0.0511 lower (95% confidence interval 0.036-0.066); p = 2 × 10−11.

How common The G allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 12, band 12q23.3 — in an intron of HCFC2.

What each result means

A/A No copy of the version the research linked to Atrial fibrillation. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Atrial fibrillation. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Atrial fibrillation. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2629755

What is rs2629755?

rs2629755 is a single position in the genome, in or near the HCFC2 gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2629755 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs2629755 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2629755 come from?

GWAS Catalog, Nature genetics 2023, PMID:36653681. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atrial fibrillation (rs2629755). MyGeneLog™. https://www.mygenelog.com/variants/rs2629755

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