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Coronary dominance (left dominant vs right dominant)

near LINC03089 · rs2624682

What the study found

Who was studied 1,167 Sub-Saharan African ancestry left dominant individuals, 8,280 Sub-Saharan African ancestry right dominant individuals.

The effect Each copy of the T allele carried 1.36 times the odds of Coronary dominance (left dominant vs right dominant) (95% confidence interval 1.23-1.5); p = 8 × 10−10.

How common The T allele had a frequency of about 58% in the people studied.

Where it sits Chromosome 10, band 10q11.21 — between genes, 76.8 kb from LINC03089.

What each result means

C/C No copy of the version the research linked to Coronary dominance (left dominant vs right dominant). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Coronary dominance (left dominant vs right dominant). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Coronary dominance (left dominant vs right dominant). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2624682

What is rs2624682?

rs2624682 is a single position in the genome, in or near the near LINC03089 gene. Published research associates it with coronary dominance (left dominant vs right dominant). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2624682 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2624682 come from?

GWAS Catalog, Cell 2025, PMID:40049164. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Coronary dominance (left dominant vs right dominant) (rs2624682). MyGeneLog™. https://www.mygenelog.com/variants/rs2624682

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