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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 318,851 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0254 lower (95% confidence interval -0.03--0.02); p = 1 × 10−22.
How common The A allele had a frequency of about 39% in the people studied.
Where it sits Chromosome 11, band 11p15.2 — in an intron of SPON1.
What each result means
A/ATwo copies of the version the research linked to Serum 25-Hydroxyvitamin D level variance. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Serum 25-Hydroxyvitamin D level variance. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Serum 25-Hydroxyvitamin D level variance. This is the starting point the study compared everyone against.
Nature communications · 2020 · PMID 32242144 · open access
Questions about rs2618515
What is rs2618515?
rs2618515 is a single position in the genome, in or near the SPON1 gene. Published research associates it with serum 25-hydroxyvitamin d level variance. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2618515 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2618515 come from?
GWAS Catalog, Nature communications 2020, PMID:32242144. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Serum 25-Hydroxyvitamin D level variance (rs2618515). MyGeneLog™. https://www.mygenelog.com/variants/rs2618515