Sensitive

Thyroid cancer

DIRC3 · rs2618148

Where this position leads

Condition: Thyroid Cancer

rs2618148 Condition: Thyroid Cancer Thyroid Cancer Condition rs2618148 rs2618148 DIRC3

What the study found

Who was studied 1,956 European ancestry cases, 101,924 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.278 higher (95% confidence interval 0.2-0.36); p = 5 × 10−12.

Where it sits Chromosome 2, band 2q35 — in an intron of DIRC3.

What each result means

C/C No copy of the version the research linked to Thyroid cancer. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Thyroid cancer. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Thyroid cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2618148

What is rs2618148?

rs2618148 is a single position in the genome, in or near the DIRC3 gene. Published research associates it with thyroid cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2618148 linked to?

On MyGeneLog this position is linked to Thyroid Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs2618148 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2618148 come from?

GWAS Catalog, JAMA network open 2022, PMID:36508215. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Thyroid cancer (rs2618148). MyGeneLog™. https://www.mygenelog.com/variants/rs2618148

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