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Phenylalanine levels

GSTA2 · rs2608627

What the study found

Who was studied 117,944 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.024 lower (95% confidence interval 0.015-0.033); p = 3 × 10−8.

How common The C allele had a frequency of about 35% in the people studied.

Where it sits Chromosome 6, band 6p12.2 — in an intron of GSTA2.

What each result means

C/C Two copies of the version the research linked to Phenylalanine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Phenylalanine levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Phenylalanine levels. This is the starting point the study compared everyone against.
Source

Questions about rs2608627

What is rs2608627?

rs2608627 is a single position in the genome, in or near the GSTA2 gene. Published research associates it with phenylalanine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2608627 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2608627 come from?

GWAS Catalog, NAR genomics and bioinformatics 2024, PMID:38711861. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Phenylalanine levels (rs2608627). MyGeneLog™. https://www.mygenelog.com/variants/rs2608627

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