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Gestational hypertension

ZNF831 · rs260017

What the study found

Who was studied 844 Asian ancestry cases, 12,098 Asian ancestry controls, 38 African ancestry cases, 1,388 African ancestry controls, 35 Hispanic or Latin American cases, 2,436 Hispanic or Latin American controls, 8,044 European ancestry cases, 169,003 European ancestry controls; replicated in 417 African ancestry cases, 7,385 African ancestry controls, 87 Hispanic or Latin American cases, 615 Hispanic or Latin American controls, 1,562 European ancestry cases, 219,863 European ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 1 × 10−13.

Where it sits Chromosome 20, band 20q13.32 — in an intron of ZNF831.

What each result means

A/A Two copies of the version the research linked to Gestational hypertension. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Gestational hypertension. That is a smaller link than two copies.
G/G No copy of the version the research linked to Gestational hypertension. This is the starting point the study compared everyone against.
Source

Questions about rs260017

What is rs260017?

rs260017 is a single position in the genome, in or near the ZNF831 gene. Published research associates it with gestational hypertension. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs260017 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs260017 come from?

GWAS Catalog, Nature medicine 2023, PMID:37248299. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Gestational hypertension (rs260017). MyGeneLog™. https://www.mygenelog.com/variants/rs260017

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