Sensitive

Myocardial infarction

ZNF831 · rs259979

Where this position leads

Condition: Myocardial Infarction

rs259979 Condition: Myocardial Infarction Myocardial Infarction Condition rs259979 rs259979 ZNF831

What the study found

Who was studied 14,825 European ancestry cases, 44,000 European and unknown ancestry cases, 2,680 cases, 380,970 European ancestry controls, 123,504 European and unknown ancestry controls, 73,242 controls.

The effect Each copy of the T allele carried 1.06 times the odds of Myocardial infarction (95% confidence interval 1.04-1.09); p = 1 × 10−8.

How common The T allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 20, band 20q13.32 — in an intron of ZNF831.

What each result means

C/C No copy of the version the research linked to Myocardial infarction. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Myocardial infarction. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Myocardial infarction. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs259979

What is rs259979?

rs259979 is a single position in the genome, in or near the ZNF831 gene. Published research associates it with myocardial infarction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs259979 linked to?

On MyGeneLog this position is linked to Myocardial Infarction. The research behind each link, and its sources, are set out on that condition page.

Does having rs259979 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs259979 come from?

GWAS Catalog, European heart journal 2021, PMID:33532862. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Myocardial infarction (rs259979). MyGeneLog™. https://www.mygenelog.com/variants/rs259979

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