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Serum 25-Hydroxyvitamin D levels

near CYP24A1 · rs2585442

What the study found

Who was studied 443,734 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0336 higher (95% confidence interval 0.029-0.038); p = 7 × 10−49.

How common The G allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 20, band 20q13.2 — between genes, 32.9 kb from CYP24A1.

What each result means

C/C No copy of the version the research linked to Serum 25-Hydroxyvitamin D levels. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Serum 25-Hydroxyvitamin D levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Serum 25-Hydroxyvitamin D levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2585442

What is rs2585442?

rs2585442 is a single position in the genome, in or near the near CYP24A1 gene. Published research associates it with serum 25-hydroxyvitamin d levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2585442 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2585442 come from?

GWAS Catalog, American journal of human genetics 2020, PMID:32059762. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum 25-Hydroxyvitamin D levels (rs2585442). MyGeneLog™. https://www.mygenelog.com/variants/rs2585442

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