Standard

HDL cholesterol

ABCA1 · rs2575876

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs2575876 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs2575876 rs2575876 ABCA1

What ClinVar records

Classification Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2018-08-30. ClinVar record 1282893 NM_005502.4(ABCA1):c.66+156C>T

What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

A/A No copy of the version the research linked to HDL cholesterol. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to HDL cholesterol. That is a smaller link than two copies.
G/G Two copies of the version the research linked to HDL cholesterol. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2575876

What is rs2575876?

rs2575876 is a single position in the genome, in or near the ABCA1 gene. Published research associates it with hdl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2575876 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs2575876 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2575876 come from?

GWAS Catalog, Circ Cardiovasc Genet 2015, PMID:26582766. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

HDL cholesterol (rs2575876). MyGeneLog™. https://www.mygenelog.com/variants/rs2575876

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