Standard

Pediatric asthma

LINC00299 · rs2561999

Where this position leads

Condition: Asthma

rs2561999 Condition: Asthma Asthma Condition rs2561999 rs2561999 LINC00299

What the study found

Who was studied 27,712 European ancestry cases, 411,131 European ancestry controls, 547 East Asian ancestry cases, 161,803 East Asian ancestry controls.

The effect Each copy of the G allele shifted the measure 0.0643 lower (95% confidence interval 0.045-0.084); p = 7 × 10−11.

Where it sits Chromosome 2, band 2p25.1 — inside LINC00299.

What each result means

A/A No copy of the version the research linked to Pediatric asthma. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Pediatric asthma. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Pediatric asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2561999

What is rs2561999?

rs2561999 is a single position in the genome, in or near the LINC00299 gene. Published research associates it with pediatric asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2561999 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs2561999 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2561999 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Pediatric asthma (rs2561999). MyGeneLog™. https://www.mygenelog.com/variants/rs2561999

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