MUC4 · rs2550250
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 74,662 European ancestry cases, 240,661 European ancestry controls.
The effect Each copy of the T allele carried 1.05 times the odds of Breakthrough COVID-19 susceptibility after at least one dose of a COVID-19 vaccine (95% confidence interval 1.03-1.07); p = 2 × 10−12.
How common The T allele had a frequency of about 44% in the people studied.
Where it sits Chromosome 3, band 3q29 — in a non-coding transcript of MUC4.
rs2550250 is a single position in the genome, in or near the MUC4 gene. Published research associates it with breakthrough covid-19 susceptibility after at least one dose of a covid-19 vaccine. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature communications 2024, PMID:39384777. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Breakthrough COVID-19 susceptibility after at least one dose of a COVID-19 vaccine (rs2550250). MyGeneLog™. https://www.mygenelog.com/variants/rs2550250