Standard

Tinnitus

GRK6 · rs2545799

What the study found

Who was studied 481,874 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 6.72 z score lower; p = 2 × 10−11.

How common The T allele had a frequency of about 46% in the people studied.

Where it sits Chromosome 5, band 5q35.3 — inside GRK6.

What each result means

G/G No copy of the version the research linked to Tinnitus. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Tinnitus. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Tinnitus. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2545799

What is rs2545799?

rs2545799 is a single position in the genome, in or near the GRK6 gene. Published research associates it with tinnitus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2545799 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2545799 come from?

GWAS Catalog, Nature communications 2024, PMID:38242899. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Tinnitus (rs2545799). MyGeneLog™. https://www.mygenelog.com/variants/rs2545799

← See all variants