LRP2 · rs2544373
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 43,148 European ancestry individuals; replicated in 1,179 Central or South Asian individuals, 1,161 African ancestry individuals.
The effect Each copy of the A allele shifted the measure 0.278 higher (95% confidence interval 0.2-0.35); p = 1 × 10−12.
How common The A allele had a frequency of about 37% in the people studied.
Where it sits Chromosome 2, band 2q31.1 — in an intron of LRP2.
rs2544373 is a single position in the genome, in or near the LRP2 gene. Published research associates it with retinal thickness (pixel 62_111). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature communications 2025, PMID:39904976. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Retinal thickness (pixel 62_111) (rs2544373). MyGeneLog™. https://www.mygenelog.com/variants/rs2544373