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REM sleep duration

KCNK9 · rs2542425

What the study found

Who was studied 80,013 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 1.21 mins/night higher (95% confidence interval 0.87-1.56); p = 7 × 10−12.

How common The T allele had a frequency of about 55% in the people studied.

Where it sits Chromosome 8, band 8q24.3 — in an intron of KCNK9.

What each result means

C/C No copy of the version the research linked to REM sleep duration. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to REM sleep duration. That is a smaller link than two copies.
T/T Two copies of the version the research linked to REM sleep duration. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2542425

What is rs2542425?

rs2542425 is a single position in the genome, in or near the KCNK9 gene. Published research associates it with rem sleep duration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2542425 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2542425 come from?

GWAS Catalog, Nature communications 2026, PMID:41922918. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

REM sleep duration (rs2542425). MyGeneLog™. https://www.mygenelog.com/variants/rs2542425

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