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Body mass index

ADCY9 · rs2540034

Where this position leads

Conditions: Childhood Body Mass Index, Obesity and Body Weight

rs2540034 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition Condition: Obesity and Body Weight Obesity and Body Weight Condition rs2540034 rs2540034 ADCY9

What the study found

Who was studied up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men; replicated in up to 10,048 Japanese ancestry women, up to 5,098 Japanese ancestry men, up to 181,999 European ancestry women, up to 140,155 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.028 higher (95% confidence interval 0.02-0.036); p = 3 × 10−12.

How common The T allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 16, band 16p13.3 — in an intron of ADCY9.

What each result means

C/C No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2540034

What is rs2540034?

rs2540034 is a single position in the genome, in or near the ADCY9 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2540034 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index, Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs2540034 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2540034 come from?

GWAS Catalog, Nature genetics 2017, PMID:28892062. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs2540034). MyGeneLog™. https://www.mygenelog.com/variants/rs2540034

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