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Waist-to-hip ratio adjusted for BMI

RN7SKP186 · rs2535326

What the study found

Who was studied 186,825 British ancestry men.

The effect Each copy of the T allele shifted the measure 0.0207 higher (95% confidence interval 0.014-0.027); p = 1 × 10−10.

Where it sits Chromosome 6, band 6p21.33 — in a non-coding transcript of RN7SKP186.

What each result means

C/C No copy of the version the research linked to Waist-to-hip ratio adjusted for BMI. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Waist-to-hip ratio adjusted for BMI. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Waist-to-hip ratio adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2535326

What is rs2535326?

rs2535326 is a single position in the genome, in or near the RN7SKP186 gene. Published research associates it with waist-to-hip ratio adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2535326 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2535326 come from?

GWAS Catalog, Scientific reports 2021, PMID:34021172. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Waist-to-hip ratio adjusted for BMI (rs2535326). MyGeneLog™. https://www.mygenelog.com/variants/rs2535326

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