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Itch intensity from mosquito bite adjusted by bite size

HLA-C · rs2523614

Where this position leads

Condition: Mosquito Bite Reaction

rs2523614 Condition: Mosquito Bite Reaction Mosquito Bite Reaction Condition rs2523614 rs2523614 HLA-C

What the study found

Who was studied 69,057 European ancestry individuals without immune related conditions.

The effect Each copy of the T allele shifted the measure 0.0237 higher (95% confidence interval 0.016-0.031); p = 6 × 10−10.

How common The T allele had a frequency of about 69% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 1 kb from HLA-B.

What each result means

C/C No copy of the version the research linked to Itch intensity from mosquito bite adjusted by bite size. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Itch intensity from mosquito bite adjusted by bite size. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Itch intensity from mosquito bite adjusted by bite size. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2523614

What is rs2523614?

rs2523614 is a single position in the genome, in or near the HLA-C gene. Published research associates it with itch intensity from mosquito bite adjusted by bite size. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2523614 linked to?

On MyGeneLog this position is linked to Mosquito Bite Reaction. The research behind each link, and its sources, are set out on that condition page.

Does having rs2523614 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2523614 come from?

GWAS Catalog, Human molecular genetics 2017, PMID:28199695. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Itch intensity from mosquito bite adjusted by bite size (rs2523614). MyGeneLog™. https://www.mygenelog.com/variants/rs2523614

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