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Philtrum width

near HOXA1 · rs2522825

What the study found

Who was studied 6,136 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.19 lower (95% confidence interval 0.13-0.26); p = 1 × 10−8.

Where it sits Chromosome 7, band 7p15.2 — between genes, 20.6 kb from HOXA1.

What each result means

C/C No copy of the version the research linked to Philtrum width. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Philtrum width. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Philtrum width. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2522825

What is rs2522825?

rs2522825 is a single position in the genome, in or near the near HOXA1 gene. Published research associates it with philtrum width. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2522825 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2522825 come from?

GWAS Catalog, PLoS Genet 2018, PMID:30067744. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Philtrum width (rs2522825). MyGeneLog™. https://www.mygenelog.com/variants/rs2522825

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