0 1812312Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3Others12Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.034 higher; p = 4 × 10−11.
Where it sits Chromosome 5, band 5q31.1 — in an intron of CARINH.
What each result means
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Low density lipoprotein cholesterol levels compared to the general population.
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Low density lipoprotein cholesterol levels.
T/TPublished research associates this genotype with typical/baseline likelihood of Low density lipoprotein cholesterol levels — no copies of the reported risk allele.
Nature genetics · 2018 · PMID 29507422 · open access
Questions about rs2522061
What is rs2522061?
rs2522061 is a single position in the genome, in or near the IRF1 gene. Published research associates it with low density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2522061 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs2522061 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2522061 come from?
GWAS Catalog, Nat Genet 2018, PMID:29507422. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1812312Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3Others12Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Low density lipoprotein cholesterol levels (rs2522061). MyGeneLog™. https://www.mygenelog.com/variants/rs2522061