Sensitive

Venous thromboembolism

ABO · rs2519093

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

Strength of the evidence

3 / 4

Its strongest genetic-study result is p = 10⁻³¹³, with 285 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10⁻⁵⁰. 2: ClinVar from one lab (1 star), or p ≤ 10⁻²⁰. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10⁻⁸). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What ClinVar records

Classification association for ABO blood group system; no assertion criteria provided (0 of 4 stars, 1 submitter), last evaluated 2021-05-01. ClinVar record 1172913 NC_000009.12:g.133266456T>C

Change history MyGeneLog™ keeps a copy of every weekly release from 2026-10-19 and compares them. This position's classification has not changed since.

What this is ClinVar's aggregate record for this position (as of its 2026-11-01 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

How common each version is

CT

Korean Korea4K

C 73.7% · T 26.3%

Korean Korea1K

C 75.8% · T 24.2%

Japanese ToMMo

C 74.3% · T 25.7%

World gnomAD

C 83.4% · T 16.6%

World TOPMed

C 83.7% · T 16.3%

By ancestry gnomAD

East Asian

C 79.5% · T 20.5%

European (non-Finnish)

C 80.5% · T 19.6%

African / African American

C 89.5% · T 10.5%

South Asian

C 84.4% · T 15.6%

Admixed American (Latino)

C 84.9% · T 15.1%

Middle Eastern

C 81.5% · T 18.5%

Finnish

C 79.1% · T 20.9%

Ashkenazi Jewish

C 78.9% · T 21.1%

The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study. The ancestry rows are gnomAD's own groups (via Ensembl), as the survey defines them, not races.

What each result means

C/C No copy of the version the research linked to Venous thromboembolism. This is the starting point the study compared everyone against.

C/T One copy of the version the research linked to Venous thromboembolism. That is a smaller link than two copies.

T/T Two copies of the version the research linked to Venous thromboembolism. That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor

Klarin D, Emdin CA, Natarajan P, Conrad MF, Kathiresan S

INVENT Consortium

Circulation. Cardiovascular genetics · 2017 · PMID 28373160

Quoting this page

Licensed CC BY-NC 4.0: free to read, share and adapt for non-commercial use, naming MyGeneLog™ and linking the exact page. Commercial use, including training or serving a commercial AI system, needs a licence — https://www.mygenelog.com/license

Venous thromboembolism (rs2519093). MyGeneLog™. https://www.mygenelog.com/variants/rs2519093

← See all variants