Sensitive

Non-small cell lung cancer

MCCD1P1 · rs2517873

Where this position leads

Condition: Lung Cancer

rs2517873 Condition: Lung Cancer Lung Cancer Condition rs2517873 rs2517873 MCCD1P1

What the study found

Who was studied 27,120 Chinese or European ancestry cases, 27,355 Chinese or European ancestry controls.

The effect Each copy of the A allele carried 1.16 times the odds of Non-small cell lung cancer (95% confidence interval 1.11-1.21); p = 5 × 10−11.

Where it sits Chromosome 6, band 6p22.1 — in an intron of MCCD1P1.

What each result means

A/A Two copies of the version the research linked to Non-small cell lung cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Non-small cell lung cancer. That is a smaller link than two copies.
G/G No copy of the version the research linked to Non-small cell lung cancer. This is the starting point the study compared everyone against.
Source

Questions about rs2517873

What is rs2517873?

rs2517873 is a single position in the genome, in or near the MCCD1P1 gene. Published research associates it with non-small cell lung cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2517873 linked to?

On MyGeneLog this position is linked to Lung Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs2517873 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2517873 come from?

GWAS Catalog, Frontiers of medicine 2021, PMID:32889700. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Non-small cell lung cancer (rs2517873). MyGeneLog™. https://www.mygenelog.com/variants/rs2517873

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