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COVID-19 (hospitalized covid vs population)

POLR1HASP · rs2517723

What the study found

Who was studied 4,702 Admixed Latin American ancestry cases, 68,573 Admixed Latin American ancestry controls, European, African, East Asian, South Asian or Admixed American individuals (See The COVID-19 Host Genetics Initiative, v7 ALL B2).

The effect Each copy of the T allele shifted the measure 0.0587 lower (95% confidence interval 0.041-0.077); p = 9 × 10−11.

Where it sits Chromosome 6, band 6p22.1 — in the 3′ untranslated region of POLR1HASP.

What each result means

C/C No copy of the version the research linked to COVID-19 (hospitalized covid vs population). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to COVID-19 (hospitalized covid vs population). That is a smaller link than two copies.
T/T Two copies of the version the research linked to COVID-19 (hospitalized covid vs population). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2517723

What is rs2517723?

rs2517723 is a single position in the genome, in or near the POLR1HASP gene. Published research associates it with covid-19 (hospitalized covid vs population). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2517723 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2517723 come from?

GWAS Catalog, eLife 2024, PMID:39361370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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COVID-19 (hospitalized covid vs population) (rs2517723). MyGeneLog™. https://www.mygenelog.com/variants/rs2517723

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