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Who was studied 74 European ancestry cases, 824 European ancestry controls.
The effect
Each copy of the G allele carried 2.95 times the odds of Diisocyanate-induced asthma (95% confidence interval 2-4.35); p = 1 × 10−8.
How common The G allele had a frequency of about 12% in the people studied.
Where it sits Chromosome 8, band 8q22.1 — in an intron of CDH17.
What each result means
A/ANo copy of the version the research linked to Diisocyanate-induced asthma. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Diisocyanate-induced asthma. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Diisocyanate-induced asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Toxicological sciences : an official journal of the Society of Toxicology · 2015 · PMID 25918132
Questions about rs2514805
What is rs2514805?
rs2514805 is a single position in the genome, in or near the CDH17 gene. Published research associates it with diisocyanate-induced asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2514805 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs2514805 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2514805 come from?
GWAS Catalog, Toxicological sciences : an official journal of the Society of Toxicology 2015, PMID:25918132. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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