1 17132326Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others6Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 771 Japanese ancestry female cases, 76,625 Japanese ancestry female controls, 28,086 European ancestry cases, 546,291 European ancestry controls.
The effect
Each copy of the G allele carried 1.07 times the odds of Pelvic organ prolapse (95% confidence interval 1.046-1.086); p = 1 × 10−11.
Where it sits Chromosome 5, band 5q23.3 — in an intron of SLC12A2.
What each result means
A/ANo copy of the version the research linked to Pelvic organ prolapse. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Pelvic organ prolapse. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Pelvic organ prolapse. That is the strongest link of the three results. A link in a study is not a diagnosis.
Communications biology · 2024 · PMID 39349682 · open access
Questions about rs251217
What is rs251217?
rs251217 is a single position in the genome, in or near the SLC12A2 gene. Published research associates it with pelvic organ prolapse. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs251217 linked to?
On MyGeneLog this position is linked to Pelvic Organ Prolapse. The research behind each link, and its sources, are set out on that condition page.
Does having rs251217 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs251217 come from?
GWAS Catalog, Communications biology 2024, PMID:39349682. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 17132326Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others6Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Pelvic organ prolapse (rs251217). MyGeneLog™. https://www.mygenelog.com/variants/rs251217