2 2321622217Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 14,988 European ancestry individuals with no NVP, 14,292 European ancestry individuals with slight NVP, 17,786 European individuals with moderate NVP, 5,445 European ancestry individuals with severe NVP, 1,220 European ancestry individuals with very severe NVP.
The effect
Each copy of the G allele shifted the measure 0.06 higher (95% confidence interval 0.043-0.076); p = 2 × 10−12.
How common The G allele had a frequency of about 20% in the people studied.
Where it sits Chromosome 11, band 11q22.1 — between genes, 44.7 kb from LOC124902737.
What each result means
A/ANo copy of the version the research linked to Severity of nausea and vomiting of pregnancy. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Severity of nausea and vomiting of pregnancy. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Severity of nausea and vomiting of pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2018 · PMID 29563502 · open access
Questions about rs2508362
What is rs2508362?
rs2508362 is a single position in the genome, in or near the PGR gene. Published research associates it with severity of nausea and vomiting of pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2508362 linked to?
On MyGeneLog this position is linked to Nausea and Vomiting of Pregnancy (Hyperemesis Gravidarum). The research behind each link, and its sources, are set out on that condition page.
Does having rs2508362 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2508362 come from?
GWAS Catalog, Nat Commun 2018, PMID:29563502. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 2321622217Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity1Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Severity of nausea and vomiting of pregnancy (rs2508362). MyGeneLog™. https://www.mygenelog.com/variants/rs2508362