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Who was studied up to 122,733 cases, up to 424,528 controls.
The effect
Each copy of the A allele shifted the measure 0.0514 higher (95% confidence interval 0.035-0.068); p = 1 × 10−9.
How common The A allele had a frequency of about 14% in the people studied.
Where it sits Chromosome 1, band 1p36.32 — in an intron of PRDM16.
What each result means
A/ATwo copies of the version the research linked to Coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Coronary artery disease. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Coronary artery disease. This is the starting point the study compared everyone against.
Circulation research · 2018 · PMID 29212778 · open access
Questions about rs2493298
What is rs2493298?
rs2493298 is a single position in the genome, in or near the PRDM16 gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2493298 linked to?
On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs2493298 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2493298 come from?
GWAS Catalog, Circ Res 2017, PMID:29212778. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2719123110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI9Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total27Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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