Standard
Response to statins (HDL cholesterol change)
CETP · rs247616
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Response to statins (HDL cholesterol change) — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Response to statins (HDL cholesterol change).
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Response to statins (HDL cholesterol change) compared to the general population.
Source
Meta-analysis of genome-wide association studies of HDL cholesterol response to statins
Postmus I,
Warren HR,
Trompet S,
Arsenault BJ,
Avery CL,
Bis JC,
Chasman DI,
de Keyser CE,
Deshmukh HA,
Evans DS,
Feng Q,
Li X
and 76 more — show all
Smit RA,
Smith AV,
Sun F,
Taylor KD,
Arnold AM,
Barnes MR,
Barratt BJ,
Betteridge J,
Boekholdt SM,
Boerwinkle E,
Buckley BM,
Chen YI,
de Craen AJ,
Cummings SR,
Denny JC,
Dubé MP,
Durrington PN,
Eiriksdottir G,
Ford I,
Guo X,
Harris TB,
Heckbert SR,
Hofman A,
Hovingh GK,
Kastelein JJ,
Launer LJ,
Liu CT,
Liu Y,
Lumley T,
McKeigue PM,
Munroe PB,
Neil A,
Nickerson DA,
Nyberg F,
O'Brien E,
O'Donnell CJ,
Post W,
Poulter N,
Vasan RS,
Rice K,
Rich SS,
Rivadeneira F,
Sattar N,
Sever P,
Shaw-Hawkins S,
Shields DC,
Slagboom PE,
Smith NL,
Smith JD,
Sotoodehnia N,
Stanton A,
Stott DJ,
Stricker BH,
Stürmer T,
Uitterlinden AG,
Wei WQ,
Westendorp RG,
Whitsel EA,
Wiggins KL,
Wilke RA,
Ballantyne CM,
Colhoun HM,
Cupples LA,
Franco OH,
Gudnason V,
Hitman G,
Palmer CN,
Psaty BM,
Ridker PM,
Stafford JM,
Stein CM,
Tardif JC,
Caulfield MJ,
Jukema JW,
Rotter JI,
Krauss RM
Journal of medical genetics · 2016 · PMID 27587472
Questions about rs247616
What is rs247616?
rs247616 is a single position in the genome, in or near the CETP gene. Published research associates it with response to statins (hdl cholesterol change). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs247616 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs247616 come from?
GWAS Catalog, J Med Genet 2016, PMID:27587472. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants