Standard
Drinks per week
KIF2A · rs247226
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,965,643 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.00672 lower (95% confidence interval 0.0049-0.0086); p = 1 × 10−12.
How common The A allele had a frequency of about 25% in the people studied.
Where it sits Chromosome 5, band 5q12.1 — in an intron of KIF2A.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Drinks per week compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Drinks per week.
G/G
Published research associates this genotype with typical/baseline likelihood of Drinks per week — no copies of the reported risk allele.
Source
Genetic diversity fuels gene discovery for tobacco and alcohol use
Saunders GRB,
Wang X,
Chen F,
Jang SK,
Liu M,
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Khunsriraksakul C,
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and 205 more — show all
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Nature · 2022 · PMID 36477530 · open access
Questions about rs247226
What is rs247226?
rs247226 is a single position in the genome, in or near the KIF2A gene. Published research associates it with drinks per week. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs247226 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs247226 come from?
GWAS Catalog, Nature 2022, PMID:36477530. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Drinks per week (rs247226). MyGeneLog™. https://www.mygenelog.com/variants/rs247226
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