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Smoking initiation

LINC02955 · rs2467111

What the study found

Who was studied 2,669,029 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.00626 higher (95% confidence interval 0.0046-0.008); p = 6 × 10−13.

How common The A allele had a frequency of about 54% in the people studied.

Where it sits Chromosome 12, band 12p12.1 — in an intron of LINC02955.

What each result means

A/A Two copies of the version the research linked to Smoking initiation. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Smoking initiation. That is a smaller link than two copies.
C/C No copy of the version the research linked to Smoking initiation. This is the starting point the study compared everyone against.
Source

Questions about rs2467111

What is rs2467111?

rs2467111 is a single position in the genome, in or near the LINC02955 gene. Published research associates it with smoking initiation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2467111 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2467111 come from?

GWAS Catalog, Nature 2022, PMID:36477530. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Smoking initiation (rs2467111). MyGeneLog™. https://www.mygenelog.com/variants/rs2467111

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