Sensitive

Breast cancer or ovarian cancer (pleiotropy)

STXBP4 · rs244353

Where this position leads

Condition: Ovarian Cancer

rs244353 Condition: Ovarian Cancer Ovarian Cancer Condition rs244353 rs244353 STXBP4

What the study found

Who was studied 122,977 breast cancer cases, 25,509 ovarian cancer cases, 146,915 controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 1 × 10−31.

Where it sits Chromosome 17, band 17q22 — in an intron of STXBP4.

What each result means

A/A No copy of the version the research linked to Breast cancer or ovarian cancer (pleiotropy). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Breast cancer or ovarian cancer (pleiotropy). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Breast cancer or ovarian cancer (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs244353

What is rs244353?

rs244353 is a single position in the genome, in or near the STXBP4 gene. Published research associates it with breast cancer or ovarian cancer (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs244353 linked to?

On MyGeneLog this position is linked to Ovarian Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs244353 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs244353 come from?

GWAS Catalog, Frontiers in microbiology 2023, PMID:36819030. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Breast cancer or ovarian cancer (pleiotropy) (rs244353). MyGeneLog™. https://www.mygenelog.com/variants/rs244353

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