Sensitive
Thyroid cancer
NRG1 · rs2439302
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Thyroid cancer — no copies of the reported risk allele.
C/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Thyroid cancer.
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Thyroid cancer compared to the general population.
Source
Discovery of common variants associated with low TSH levels and thyroid cancer risk
Gudmundsson J,
Sulem P,
Gudbjartsson DF,
Jonasson JG,
Masson G,
He H,
Jonasdottir A,
Sigurdsson A,
Stacey SN,
Johannsdottir H,
Helgadottir HT,
Li W
and 35 more — show all
Nagy R,
Ringel MD,
Kloos RT,
de Visser MC,
Plantinga TS,
den Heijer M,
Aguillo E,
Panadero A,
Prats E,
Garcia-Castaño A,
De Juan A,
Rivera F,
Walters GB,
Bjarnason H,
Tryggvadottir L,
Eyjolfsson GI,
Bjornsdottir US,
Holm H,
Olafsson I,
Kristjansson K,
Kristvinsson H,
Magnusson OT,
Thorleifsson G,
Gulcher JR,
Kong A,
Kiemeney LA,
Jonsson T,
Hjartarson H,
Mayordomo JI,
Netea-Maier RT,
de la Chapelle A,
Hrafnkelsson J,
Thorsteinsdottir U,
Rafnar T,
Stefansson K
Nature genetics · 2012 · PMID 22267200
Questions about rs2439302
What is rs2439302?
rs2439302 is a single position in the genome, in or near the NRG1 gene. Published research associates it with thyroid cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2439302 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2439302 come from?
GWAS Catalog, Nat Genet 2012, PMID:22267200. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants