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Anti-polyomavirus 2 IgG seropositivity

FUT2 · rs2432132

What the study found

Who was studied 8,735 White British ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.06 lower (95% confidence interval 0.044-0.076); p = 9 × 10−15.

How common The C allele had a frequency of about 38% in the people studied.

Where it sits Chromosome 19, band 19q13.33 — in the 3′ untranslated region of FUT2.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Anti-polyomavirus 2 IgG seropositivity compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Anti-polyomavirus 2 IgG seropositivity.
T/T Published research associates this genotype with typical/baseline likelihood of Anti-polyomavirus 2 IgG seropositivity — no copies of the reported risk allele.
Source

Questions about rs2432132

What is rs2432132?

rs2432132 is a single position in the genome, in or near the FUT2 gene. Published research associates it with anti-polyomavirus 2 igg seropositivity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2432132 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2432132 come from?

GWAS Catalog, Open Forum Infect Dis 2020, PMID:33204752. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Anti-polyomavirus 2 IgG seropositivity (rs2432132). MyGeneLog™. https://www.mygenelog.com/variants/rs2432132

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