Standard

C-reactive protein levels

SLC38A4 · rs2429473

Where this position leads

Condition: C-Reactive Protein Levels

rs2429473 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs2429473 rs2429473 SLC38A4

What the study found

Who was studied 575,531 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.022 higher (95% confidence interval 0.016-0.028); p = 1 × 10−18.

Where it sits Chromosome 12, band 12q13.11 — in an intron of SLC38A4.

What each result means

A/A Two copies of the version the research linked to C-reactive protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to C-reactive protein levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to C-reactive protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs2429473

What is rs2429473?

rs2429473 is a single position in the genome, in or near the SLC38A4 gene. Published research associates it with c-reactive protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2429473 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs2429473 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2429473 come from?

GWAS Catalog, Nature communications 2022, PMID:35459240. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

C-reactive protein levels (rs2429473). MyGeneLog™. https://www.mygenelog.com/variants/rs2429473

← See all variants