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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 10,530 European, Hispanic or African American individuals; replicated in up to 2,466 African American individuals, up to 15,619 European ancestry individuals, 1,734 Hispanic ancestry children.
The effect
Each copy of the T allele shifted the measure 0.139 higher (95% confidence interval 0.1-0.17); p = 3 × 10−15.
How common The T allele had a frequency of about 20% in the people studied.
Where it sits Chromosome 20, band 20q13.12 — in an intron of SLC13A3.
What each result means
C/CNo copy of the version the research linked to Metabolite levels (malate; cmh_malate; Malate). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Metabolite levels (malate; cmh_malate; Malate). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Metabolite levels (malate; cmh_malate; Malate). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2023 · PMID 37253714 · open access
Questions about rs2425880
What is rs2425880?
rs2425880 is a single position in the genome, in or near the SLC13A3 gene. Published research associates it with metabolite levels (malate; cmh_malate; malate). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2425880 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2425880 come from?
GWAS Catalog, Nature communications 2023, PMID:37253714. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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